On the radio the other day, someone said "Uranus" in such a way that it sounded like an adjective, "urinous." According to Wikipedia, that's actually the earliest of the current common English pronunciations; I had always thought it was a new pronunciation chosen to avoid sounding like "your anus," but Wikipedia says it was the other way around.
Wikipedia also mentions a third pronunciation that looks like it would sound more or less like "you ran us," which avoids both of the off-color homonyms. Fair enough.
But I would like to propose yet another pronunciation, to both avoid the homonyms and make clear how silly the whole thing is: oo-RAAAAHN-oos. (In ASCII IPA: /u 'rAA nus/.)
It's important to hold that second syllable, making the whole thing sound sort of like a war cry. In fact, ideally the word would be sort of half-sung while charging into battle.