According to an article by Fern Riddell, Mary Wollstonecraft Shelley once wrote to a friend:
I was so ready to give myself away—and being afraid of men, I was apt to get tousy-mousy for women.
Apparently (according to that same article), tuzzy-muzzy is “slang for the vagina,” dating back to 1642.
Only one of my five slang dictionaries (Partridge’s 8th, 1984) lists either of those terms; it defines tuzzy-muzzy or tuzzi-muzzy or tuzzymuzzy as “the female pudend,” dating back to 1710. The Shorter OED also lists tuzzy-muzzy or tussie-mussie with the same meaning, along with an alternative meaning: a bunch of flowers. (And tussy by itself means, essentially, “tousled.”)
Surely Shelley just meant that she liked to buy flowers for women! …Okay, maybe not.
I do think it’s interesting, though, that she used the phrase get tousy-mousy for; I’m certainly willing to believe that that phrase is sexual slang, and I get the general idea of what she seems to have meant, but the exact meaning of her usage doesn’t seem obvious to me if tousy-mousy refers to genitalia per se.