MyDoom
I gather that, theoretically, MyDoom is supposed to stop sending itself on 12 February. I'm looking forward to that, and hoping the next similar worm doesn't show up for a while. At this point I'm getting about one copy of MyDoom every two minutes, including the copies that arrive in bounces. (Down from one copy a minute a few days ago.)
But I'm counting my blessings: Kent said over on the Rumor Mill that at peak volume, he was getting a hundred copies a minute, plus the associated bounces. The volume I'm seeing is already way too much; I think if I were getting two hundred times this much I'd have turned off my email by now.